The research analyzes the current status of consumption of fresh and processed sea crabs in 3 big cities of Can Tho, Ho Chi Minh and Hanoi, and finds out the relationship among groups of factors affecting the customer intention of buying fresh and processed sea crabs by using Cronbach’s Alpha test and Exploratory Factor Analysis (EFA). The analysis of 134 consumers shows that there is an average of 2.1 times/year of buying fresh crabs, 3.5kg/household/year of tomalley fat crabs, 5.1kg/household/year of male crabs, and 6kg/household/year of 1-pincer crabs (cua xô). Most consumers purchase fresh sea crabs from traditional markets to boil and cook hotpot. There are two groups of factors affecting the buy intention: perception of nutrition and perception of convenience of use. For processed sea crabs, 58.96% of the consumers have known, 17.16% have bought, and 68.6% have intended to buy. For canned crab meat, 43% of the customers have bought and supermarkets are the distribution channel that they buy the most, accounting for 47.83%. There are 3 groups of factors affecting the consumption intention of processed crabs: perception of health, perception of price and accessibility, and perception of convenience of use. These findings can help seafood processing companies introduce their processed sea crab products to market, thereby contributing to the effective of the development of the crab supply chain in the Mekong Delta.