Lettuce is cultivated as a leaf vegetable sometimes for seeds and stem. Most lettuce varieties are eaten fresh and commonly served as the base of green salads. Thus, this study employed an alternative of the fermented plant juice (FPJ) in an instance of intercepting something to banana peel (BP), Arachis pintoi (AP), and Trichantea gigantea (TG). The additives of coco-water (CW) appear in BP+AP+TG, and types of nutrient solution (CNS) with the outcome on the hydroponic system of growth and yield of lettuce. The experiment was laid out following a Simple Factor arranged in RCBD with three replications and have five (5) samples per treatment per replication. The following treatments were evaluated as T1 - CW; T2 - CNS; T3 - BP+C; T4 - AP+CW; T5 - TG+CW; T6 - BP+AP (1:1)+CW; T7 - AP+TG(1:1)+CW; T8 - TG+BP(1:1)+CW; and T9 - AP+BP+TG(1:1:1)+CW. The results a significant effect on the plant height (taller height), number of leaves (more leaves), the diameter of leaves (wider leaver), and length of leaves (longer leaves) of the treatments by nutrient solution (T2) of lettuce. The T2 was comparable effect T1 but among in the treatments of the BP, AP, and TG in lettuce. The root length and root dry weight were a significant effect on the longer of roots to length and denser of the dried weight roof of T2 in the treatment of lettuce, respectively. The yield that nutrient solution (T2) had achieved the more immeasurable yield of lettuce. It shows T2 and T1 were 11.14 and 7.98 ton/ha; respectively, acquired comparable effect in the treatments of high yield of lettuce.